On November 9th we started Sadie back on her medication. The ASPCA website says that it needs to be administered for at least six weeks before behavior change. Sadie has been marking the doors in the house; our front door, garage door and on occasion the sliding doors to the deck. Females marking could be caused due to territorial issues or issues with other cats in the household. Sassy doesn't have a mean bone in her body. We've never seen her aggressively go after Sadie. That's not to say it doesn't happen when we aren't looking but it's been almost two years we've had them together. We're not sure what Sadie's issues are, but we're both tired of cleaning up after her.
Sassy seems to have regressed, also. She had been doing so well with the litter boxes that we quit looking for messes and now she's started making them again. 95% of the time her messes are on the mats we put down under the litter boxes, but one was actually on the carpet. I purchased three bottles of essential oils: lemon, eucalyptus and lavender. We've cleaned the areas that both cats mess on and then sprinkled them with one of the three essential oils. We started that about four days ago. Today, for the second day, we have no messes, both cats are going where they are supposed to go.
Sadie has been a little aggressive since we restarted her meds. You have a 50/50 chance of being able to pet her. First she will growl, then hiss and then put out her claws. I'm usually gone at the growl but she did walk up between us in bed last night - a first since 11/9. She used to wake us up by licking our hands or, in my case, my hair, but she hasn't done that since we started her meds. An adjustment period, to be sure.